Open Access Revisão por pares

Review Article - Year 2026 - Volume 41Issue 1

Technical Differentiation and Innovation in Contemporary Liposuction: A Critical Study of the Postoperative Period in Light of New Technologies

Diferenciação técnica e inovação na lipoaspiração contemporânea: Estudo crítico do pós-operatório frente a novas tecnologias

http://www.dx.doi.org/10.1055/s-0046-1820097

ABSTRACT

Plastic surgery is a medical specialty in constant transformation, driven by the introduction of new techniques and technologies. In recent years, there has been a notable increase in public interest in esthetic procedures targeting body contouring, particularly liposuction, which remains among the most popular options worldwide. An analysis of Google Trends data revealed the search behavior for liposuction throughout the past 12 months. Interest in this procedure remained high throughout the period, with relevance scores ranging from 50 to 100%. Furthermore, there was a notable increase in queries on liposuction technologies. The search for Argoplasma technology increased 400%, while the search for high-definition liposuction experienced a 200% growth. This data reinforces the persistence of liposuction as a prominent procedure and indicates a clear trend toward the appreciation of advanced technological resources in the context of plastic surgery. In this scenario, it becomes essential to discuss the impacts of these innovations and to evaluate their contributions to the efficacy, safety, and quality of the outcomes of liposuction procedures in the contemporary clinical practice, particularly in terms of the postoperative management and its impact.

Keywords: lipectomy; biomedical technology; plastic surgery procedures

RESUMO

A cirurgia plástica é uma especialidade médica em constante transformação, impulsionada pela introdução de novas técnicas e tecnologias. Nos últimos anos, esse campo tem acompanhado um aumento significativo no interesse do público por procedimentos estéticos voltados ao contorno corporal, especialmente a lipoaspiração, que continua entre os mais procurados no cenário mundial. Com base em dados obtidos por meio da ferramenta Google Trends, foi possível analisar o comportamento das buscas pelo termo lipoaspiração nos últimos 12 meses. O interesse por esse procedimento manteve-se elevado durante todo o período, com índices de relevância que variaram entre 50 e 100%. Além disso, observou-se um crescimento expressivo nas buscas relacionadas a tecnologias associadas à lipoaspiração. A tecnologia de Argoplasma apresentou aumento de 400% nas buscas, ao passo que a lipoaspiração de alta definição teve um crescimento de 200%. Esses dados reforçam a permanência da lipoaspiração como procedimento de destaque, e também apontam para uma tendência clara de valorização de recursos tecnológicos avançados no contexto da cirurgia plástica. Diante disso, torna-se essencial discutir os impactos dessas inovações, e avaliar suas contribuições para a eficácia, segurança e qualidade dos resultados obtidos com os procedimentos lipoaspiratórios na prática clínica contemporânea, principalmente a condução pós-operatória e seu impacto.

Palavras-chave: segurança do paciente; cuidados pós-operatórios; lipectomia; tecnologia biomédica; procedimentos de cirurgia plástica


Introduction

Techniques for abdominal and body contouring have benefit-ed significantly from advances in new technologies, includ-ing laser-, ultrasound-, and radiofrequency-based devices, which promote greater contraction of fibrous septa and the dermis. In addition, fat-grafting techniques have emerged as important allies in the improvement of surgical outcomes, particularly with the development of new approaches for fat processing and enhanced integration into recipient tissues. Despite these promising advances, robust scientific evidence supporting the efficacy and safety of these innovations remains scarce. Furthermore, few studies have addressed technology-specific periand postoperative care. This gap highlights the need for more comprehensive investigations to validate these procedures and establish standardized clinical protocols.

Review

Vibration amplification of sound energy at resonance (VASER) technology has demonstrated significant advances in body contouring using liposuction. In a retrospective analysis of 175 consecutive cases,1 all treated areas im-proved, with high levels of patient satisfaction. In the high-definition (HD) liposuction group, there was no need for fat grafting to achieve well-defined anatomical contours. For gynecomastia, the VASER technique enabled effective treat-ment with reduced tissue excision. Furthermore, postopera-tive recovery was generally uneventful, with a low incidence of reported complications.1

As an adjunctive technology to liposuction, Renuvion has shown promising clinical outcomes in promoting skin retraction. A clinical series involving 64 cases2 noted signifi-cant improvements in skin quality and body contour defini-tion, even in areas with marked laxity. The application of helium plasma resulted in visible immediate tissue contrac-tion, with evidence of progressive collagen reorganization during the postoperative period. Moreover, it had a satisfac-tory safety profile, with a low rate of complications and rapid patient recovery.2

In a retrospective study, Tettamanzi et al.3 evaluated the effectiveness of radiofrequency-assisted liposuction (RFAL) using BodyTite technology in arm-lifting procedures. The sample included patients presenting with upper-limb skin laxity who were not yet ideal candidates for conventional brachioplasty. The study demonstrated that BodyTite appli-cation resulted in significant dermal contraction and visible contour improvement, without the need for extensive inci-sions. The authors3 reported high patient satisfaction from esthetic and functional perspectives. Moreover, the compli-cation rates were minimal, and postoperative recovery was considered rapid and well-tolerated. This study supports the growing adoption of minimally-invasive technologies to treat skin laxity, particularly among patients seeking effec-tive results with reduced morbidity. Bipolar radiofrequency proved to be a safe and efficient alternative for arm lifting, and it may replace traditional surgical procedures in proper-ly-selected cases. It is key to consider incorporating this approach in clinical protocols aimed at achieving consistent esthetic outcomes with greater postoperative comfort.

The combination of the Morpheus8 (InMode) device with HD liposuction has emerged as one of the most promising approaches in modern plastic surgery to improve body contour with minimal invasiveness. The Morpheus8 integra-tes fractional microneedling with bipolar radiofrequency, promoting deep dermal and subcutaneous heating, which results in collagen stimulation and significant tissue contrac-tion. Hoyos et al.4 retrospectively analyzed 86 patients who underwent the dynamic definition liposculpture (HD2) tech-nique combined with the Morpheus8 device, reporting ef-fective skin retraction, high patient satisfaction, and minimal complications. The protocol included device application immediately after liposuction, enhancing the synergistic effect between the anatomical definition provided by HD techniques and the tightening effect of fractional radiofre-quency. This technology demonstrated particularly favorable results in areas such as the abdomen, flanks, and arms, in which skin retraction is critical for esthetic outcomes. Fur-thermore, the authors4 emphasized that the association of technologies such as the Morpheus8 contributes to greater durability of the results, reduces residual laxity, and enhan-ces procedural safety. This technological integration repre-sents a crucial advance in refining HD liposuction, and it is becoming an emerging standard in body-contouring procedures.

Argon plasma (Argoplasma) has gained prominence as an adjunctive technology in minimally-invasive esthetic proce-dures, particularly for skin retraction following liposuction. Despite the increase in liposuction procedures that use Argoplasma (which are the most sought-after, according to Google Trends [Alphabet Inc.] data) as a complementary technology, a significant scarcity of indexed scientific pub-lications supporting its efficacy and safety under rigorous methodological criteria remains evident. In the esthetic practice, subdermal Argoplasma is primarily described in non-indexed materials and unpublished scientific presenta-tions, highlighting the urgent need for randomized, con-trolled clinical trials with longitudinal follow-up to scientifically substantiate the benefits attributed to this technique in the context of postliposuction skin retraction.

A prospective, non-randomized clinical trial registered in April 2025 aims to investigate the effects of the Quantum RF (InMode) radiofrequency probe on subdermal retraction and skin rejuvenation in patients undergoing HD liposculpture. The protocol was registered on Clinical Trials.gov (NCT06958978).5 The primary outcomes include objective assessments of skin elasticity, cutaneous reactivity, and patient satisfaction, measured at 1, 3, and 6 months postop-eratively. Although promising, this technique still lacks published clinical evidence in peer-reviewed scientific jour-nals. Therefore, completion of this trial and further studies are required, given the pioneering nature of this technology.

Thermal-induced skin retraction has been studied exten-sively in plastic surgery and orthopedic rehabilitation due to its potential for tissue remodeling. Controlled heat applica-tion promotes the partial denaturation of collagen fibers, leading to the immediate contraction of existing collagen. Next, it stimulates fibroblasts and neocollagenesis, a fundamental process for skin firmness and regeneration. An experimental study by Hayashi et al.6 showed that thermal heating of the glenohumeral joint capsule resulted in signifi-cant changes in the length and histological properties of collagen. The authors observed tissue retraction associated with the reorganization of collagen fibers and the subse-quent biological healing response, with evidence of new collagen synthesis. These findings reinforce the therapeutic applicability of heat in esthetic and medical procedures aimed at skin retraction and improvement of dermal quality through the reorganization of the collagenous framework. Therefore, controlled therapeutic heat is a promising tool to induce contraction and regeneration of the extracellular matrix, contributing to positive clinical results in medical esthetics and deep tissue physical therapy.6

Hayashi et al.6 also demonstrated that the thermal re-sponse of the articular capsular tissue depends on the temperature increase, with significant changes starting at 65 °C. The experiment showed that groups exposed to 70 °C, 75 °C, and 80 °C presented a statistically significant reduc-tion in the length of the articular capsule after treatment, indicating effective collagen contraction. A histological anal-ysis further revealed collagen hyalinization, a clear sign of denaturation and fibrillar reorganization, in groups exposed to 65 °C, 70 °C, 75 °C, and 80 °C. These data confirm that temperatures 2: 65 °C induce marked structural alterations in collagen fibers, with progressively-greater effects at higher temperatures. The correlation between the degree of physical contraction and histological hyalinization rein-forces the understanding that the efficacy of thermal heating for tissue contraction strongly depends on temperature. Such evidence is fundamental to standardize clinical proto-cols to use therapeutic heat, be them via radiofrequency, ultrasound, or laser, to achieve safe and effective skin con-traction and collagen induction in esthetic and reconstruc-tive treatments.

The literature contains comprehensive discussions on thermal safety in surgical settings, particularly regarding the prevention of perioperative hypothermia and the strict environmental control required in operating rooms. In a narrative review, Ji et al.7 highlighted that temperatures below 21 °C significantly increase the risk of intraoperative hypothermia, emphasizing the need for precise monitoring of the patient’s core temperature through esophageal, naso-pharyngeal, or tympanic routes, as well as the use of active warming methods during procedures.7 Moreover, in a sys-tematic review, Katz8 consolidated key recommendations from entities such as the Centers for Medicare and Medicaid Services (CMS), the American Society of Heating, Refrigerat-ing and Air-Conditioning Engineers (ASHRAE), Joint Com-mission, and the American Society of Anesthesiologists (ASA), which advocate maintaining operating room temper-atures between 20 and 23 °C, relative humidity from 20 to 60%, positive pressure, and at least 20 air changes per hour, thereby reducing infection risk and ensuring greater intra-operative thermal stability.8

The thermal-guided technique for lipolysis and skin contraction using a 980-nm diode laser represents a significant advancement in minimally-invasive procedures, combining clinical efficacy with intraoperative thermal safety. Kama-moto et al.9 observed that the use of an infrared thermome-ter for continuous monitoring of the cutaneous surface temperature during laser application in the operating room enabled the skin to be maintained below 42 °C, signifi-cantly reducing the risk of dermal burns and thermal injury to adjacent tissues. In addition to direct thermal control over the patient, the surgical environment was kept within strict technical parameters, with room temperature ranging from 20 to 23 °C, relative humidity between 30 and 60%, and a ventilation system with at least 20 air exchanges per hour, in accordance with Brazilian Health Regulatory Agency (Agên-cia Nacional de Vigilância Sanitária, ANVISA, in Portuguese) regulations (Resolution of the Collegiate Board [Resolução da Diretoria Colegiada, RDC, in Portuguese] number 50/2002).10 These environmental factors are crucial to ensure thermal stability during laser use, as they contribute to the safe dissipation of generated heat while maintaining thermal comfort and biosafety. The standardization of thermal con-trol in the skin and the environment, combined with the surgeon’s experience, constitutes a critical factor in prevent-ing burns, particularly in anatomical areas with thinner subcutaneous tissue. Thus, thermoguidance consolidates itself as a valuable tool in the body-contouring technological arsenal, promoting selective fat destruction and skin con-traction with high predictability and low complication rates.

Taha et al.11 analyzed the necessity and effectiveness of postoperative drains in 50 male patients who underwent liposuction assisted by Lipomatic (Euromi S.A.) and VASER technologies after tumescent infiltration. The mean age of the patients was 35 years (range: 21-50) years, and the mean body mass index, 29 (range: 28-33) kg/m2. The patients were divided into two groups: group A consisted of 25 subjects who did not undergo adjunctive drainage procedures, and group B comprised 25 patients who underwent postopera-tive drainage. Follow-up was performed every other day for 3 weeks to detect seromas. The results indicated that the routine use of drains correlates with a significant reduction in the incidence of seromas, hematomas, or infections when compared to no drains, provided that other effective strategies, such as proper compression and manual lymphatic drainage, were employed. However, drain use was associated with greater discomfort and prolonged hospital stay. The authors11 suggest a tailored drain indication according to the extent of the treated area and the clinical evaluation, rather than its systemic application. Additionally, they emphasize that HD liposuction requires technical rigor from the surgeon and patient compliance to optimize the esthetic outcomes. When indicated, drainage procedures and drain placement are effec-tive in minimizing seroma formation, accelerating recovery, and improving outcomes, highlighting the significance of personalized postoperative protocols for this technique.11

Chi et al.12 conducted a trial with 20 patients undergoing abdominoplasty combined with liposuction, divided into a control group and an experimental group, the latter under-going, immediately after surgery, lymphatic taping in a fan pattern over the surgical areas, assessing the presence of ecchymoses in different regions of the abdomen and flanks on postoperative days 3, 7, and 14. The results demonstrated that the experimental group exhibited a significant reduc-tion in ecchymosis formation compared with the control group, particularly in the right flank, epigastric, and hypogastric regions. This finding suggests that the technique promotes lymphatic return and decreases blood extravasa-tion into tissues. Accordingly, the use of lymphatic taping after abdominal surgeries may represent an effective and noninvasive strategy to reduce complications such as ecchy-moses, contributing to the esthetic and functional recovery of the patients.12

Conclusion

Robust studies establishing effective and standardized post-operative protocols in plastic surgery remain scarce, particularly given the increasing incorporation of new tech-nologies in the field. Although technological advancements offer evident benefits, it is essential that the attending professional conducts the clinical practice with critical and careful judgment, performing a thorough evaluation of the patient’s skin. This assessment is crucial, as the skin may exhibit early signs of potential burns resulting from the high temperatures employed for collagen contraction. Even with the safety measures in place, increased thermal exposure can trigger a more significant inflammatory response, which may lead to greater edema and potentially heighten the risk of complications such as seroma and fibrosis. Therefore, careful clinical management becomes indispensable to min-imize these adverse effects and optimize postoperative recovery, underscoring the urgent need for research that validates and standardizes safe and effective protocols for the use of these technologies in plastic surgery.

References

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5. ClinicalTrials.gov. Effects of QUANTUM Probe for Skin Rejuvena-tion and Subdermal Retraction in Patients Undergoing High-Definition Liposculpture [Internet]. NCT06958978. Available from: https://clinicaltrials.gov/study/NCT06958978

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1. Aesthetics and Cosmetology Course Universidade Regional Integrada do Alto Uruguai e das Missões, Erechim, RS, Brazil

Financial Support

The authors declare that they did not receive financial support from agencies in the public, private, or non-profit sectors to conduct the present study.

Address for correspondence Nágila Bernarda Zortéa, Curso de Medicina, Universidade Regional Integrada do Alto Uruguai e das Missões, Erechim, Rio Grande do Sul, Brazil (e-mail: nagilazortea@uricer.edu.br).

Artigo submetido: 31/07/2025.
Artigo aceito: 13/01/2026.

Editor-in-Chief: Dov Charles Goldenberg.

Conflict of Interests

The author has no conflict of interests to declare.